Granzymes

A family of serine endopeptidases found in the SECRETORY GRANULES of LEUKOCYTES such as CYTOTOXIC T-LYMPHOCYTES and NATURAL KILLER CELLS. When secreted into the intercellular space granzymes act to eliminate transformed and virus-infected host cells.

Also Known As:

Granzyme; Granzyme A; Granzyme B; Cytotoxic Serine Protease B; Cytotoxic T-Lymphocyte Associated 1 Protein; Cytotoxic T-Lymphocyte Proteinase 1; Fragmentin 2; Granzyme C; Granzyme K; Granzyme M; Granzyme-3; Granzyme-Like Protein III; Hanukah Factor; NK-Tryptase-2; Natural Killer Cell Granule Tryptase-2; Cytotoxic T Lymphocyte Associated 1 Protein; Cytotoxic T Lymphocyte Proteinase 1; Granzyme 3; Granzyme Like Protein III; NK Tryptase 2; Natural Killer Cell Granule Tryptase 2

Pharmalogical Action Categories:

Cytotoxins

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Serine Proteases: 3726
        Serine Endopeptidases: 11
        Granzymes: 2238
      - Endopeptidases: 633
        Serine Endopeptidases: 11
        Granzymes: 2238

R H Fernando Selected Research

R H Fernando Research Topics

Disease

Drug/Important Bio-Agent (IBA)